首页> 外文OA文献 >Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites.

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Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites.

机译：Mithramycin A通过Sp1位点下调XIAP基因启动子使癌细胞对TRAIL介导的细胞凋亡敏感。

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Lee, TJ; Jung, EM; Lee, JT; Kim, S; Park, JW; Choi, KS; Kwon, TK;
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年度 2011
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1. Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis [J] . Felix Rückert, Nicole Samm, Anne-Kathrin Lehner, BMC Cancer . 2010,第1期

机译：Bcl-2，XIAP和Survivin的同时基因沉默使胰腺癌细胞对凋亡重新敏感
2. E1A oncogene expression inhibits PTHrP P3 promoter activity and sensitizes human prostate cancer cells to TNF-induced apoptosis. [J] . Asadi FK, Kukreja SC, Boyer B, International Urology and Nephrology . 2010,第4期

机译：E1A癌基因表达抑制PTHrP P3启动子活性，并使人前列腺癌细胞对TNF诱导的细胞凋亡敏感。
3. E1A oncogene expression inhibits PTHrP P3 promoter activity and sensitizes human prostate cancer cells to TNF-induced apoptosis [J] . Farrokh K. Asadi, Subhash C. Kukreja, Brigitte Boyer, International Urology and Nephrology . 2010,第4期

机译：E1A癌基因表达抑制PTHrP P3启动子活性并使人前列腺癌细胞对TNF诱导的细胞凋亡敏感
4. A Novel Small-Molecule IAP Antagonist, AZD5582, Draws Mcl-1 Down-Regulation for Induction of Apoptosis Through Targeting of cIAP1 and XIAP in Human Pancreatic Cancer [C] . Ih-Yeon Hwang, Seul Lee, Jai-Hee Moon, International Molecular Medicine Tri-Conference. . 2016

机译：一种新型的小分子IAP拮抗剂AZD5582，通过靶向CIAP1和XIAP在人胰腺癌中诱导诱导细胞凋亡的MCL-1下调
5. p53- and p73-mediated transcriptional repression of the cyclin B1 promoter is dependent on functional Sp1 DNA binding sites. [D] . Innocente, Steven A. 2005

机译：细胞周期蛋白B1启动子的p53和p73介导的转录抑制取决于功能性Sp1 DNA结合位点。
6. Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis (XIAP) and sensitizes prostate cancer cells to TRAIL-mediated apoptosis [O] . Peter Makhov, Konstantin Golovine, Robert G. Uzzo, -1

机译：锌螯合诱导X连锁凋亡抑制剂（XIAP）的快速耗竭并使前列腺癌细胞对TRAIL介导的凋亡敏感
7. Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells [O] . Y.-H. Kim 2004

机译：丁酸钠通过在结肠癌细胞中通过SP1位点诱导来自DR5基因启动子的转录来敏化甲状腺介导的细胞凋亡
8. Regulation of TRAIL-Mediated Apoptosis in Prostate Cancer by Overexpression in XIAP [R] . Bonavida, B. 2004

机译：通过XIap过表达调节TRaIL介导的前列腺癌细胞凋亡

Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites.

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